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Merck

M8574

Sigma-Aldrich

D-(+)-Manosa

synthetic, ≥99% (GC)

Sinónimos:

D-mannopiranosa

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About This Item

Fórmula empírica (notación de Hill):
C6H12O6
Número de CAS:
Peso molecular:
180.16
Beilstein:
1564373
Número CE:
Número MDL:
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
NACRES:
NA.25

origen biológico

synthetic

Nivel de calidad

Análisis

≥99% (GC)

formulario

powder

actividad óptica

[α]25/D 13.5 to 14.9 °, c = 4% (w/v) in water

técnicas

gas chromatography (GC): suitable

color

white to off-white

mp

133-140 °C (lit.)

solubilidad

water: soluble 10 g/L at 20 °C

temp. de almacenamiento

room temp

cadena SMILES

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

Clave InChI

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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Aplicación

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.

Acciones bioquímicas o fisiológicas

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

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Simone Torretta et al.
Nature communications, 11(1), 6343-6343 (2020-12-15)
D-mannose is a monosaccharide approximately a hundred times less abundant than glucose in human blood. Previous studies demonstrated that supraphysiological levels of D-mannose inhibit tumour growth and stimulate regulatory T cell differentiation. It is not known whether D-mannose metabolism affects
Brett Shannon et al.
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5074-5082 (2014-04-25)
HSV-2 infection is common and generally asymptomatic, but it is associated with increased HIV susceptibility and disease progression. This may relate to herpes-mediated changes in genital and systemic immunology. Cervical cytobrushes and blood were collected from HIV-uninfected African/Caribbean women in
Charles D Murin et al.
Journal of virology, 88(17), 10177-10188 (2014-06-27)
The neutralizing anti-HIV-1 antibody 2G12 is of particular interest due to the sterilizing protection it provides from viral challenge in animal models. 2G12 is a unique, domain-exchanged antibody that binds exclusively to conserved N-linked glycans that form the high-mannose patch
Ana Sofia Carvalho et al.
Molecular & cellular proteomics : MCP, 13(12), 3294-3307 (2014-08-17)
We investigated the molecular effects of glucosamine supplements, a popular and safe alternative to nonsteroidal anti-inflammatory drugs, for decreasing pain, inflammation, and maintaining healthy joints. Numerous studies have reported an array of molecular effects after glucosamine treatment. We questioned whether
Varnica Khetrapal et al.
Nucleic acids research, 43(13), e83-e83 (2015-03-25)
Creation of defined genetic mutations is a powerful method for dissecting mechanisms of bacterial disease; however, many genetic tools are only developed for laboratory strains. We have designed a modular and general negative selection strategy based on inducible toxins that

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