905H-0

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit Monoclonal Antibody

• Sinónimos: Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse; rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: EP1601Y + LL002, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulario: buffered aqueous solution
• reactividad de especies: human
• envase: bottle of 1.0 mL predilute (905H-07); bottle of 7.0 mL predilute (905H-08)
• fabricante / nombre comercial: Cell Marque^™
• concentración: 0.1-1.5 μg/mL (predilute)
• isotipo: IgG3; IgG
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: human ... KRT5(3852)

Descripción

Descripción general

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.

Calidad

IVD

IVD

IVD

RUO

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

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Otras notas

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Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany