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Key Documents

179M-9

Sigma-Aldrich

CD79a (JCB117) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

JCB117, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (179M-94)
vial of 0.5 mL concentrate (179M-95)
bottle of 1.0 mL predilute (179M-97)
vial of 1.0 mL concentrate (179M-96)
bottle of 7.0 mL predilute (179M-98)

fabricante / nombre comercial

Cell Marque

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG1κ

control

tonsil

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

membranous

Información sobre el gen

human ... CD79A(973)

Descripción general

Anti-CD79a is a B-cell marker that is generally used to complement CD20. This antibody will stain many of the same lymphomas as CD20, but also is more likely to stain precursor B-lymphoid leukemias than CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Anti-CD79a will stain many cases of acute promyelocytic leukemia (FAB-M3), but only rarely stains other types of myeloid leukemia.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

CD79a Positive Control Slides, Product No. 179S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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D Y Mason et al.
European journal of immunology, 22(10), 2753-2756 (1992-10-01)
Surface immunoglobulin on mouse B cells is associated with a heterodimer comprising the products of the mb-1 and B29 genes. Here we report that antibodies raised against a peptide sequence from the intracytoplasmic C terminus of the B29 murine gene
X Yao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(2), 105-110 (2001-03-10)
Immunohistochemical studies are increasingly used for the routine diagnosis of lymphomas as it is widely accepted that lymphomas of different cell lineages vary in their prognosis and response to therapy. A case of peripheral T-cell lymphoma with aberrant expression of
K Blakolmer et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(7), 766-772 (2000-07-27)
The monoclonal antibodies L26 (CD20) and CD79a are very useful reagents for the immunohistochemical assessment of B-cell lineage in lymphoproliferative disorders. Although very few CD20-positive peripheral T-cell lymphomas (PTL) have been reported, comprehensive analyses of CD79a reactivity in extranodal PTL
B T Lin et al.
Human pathology, 28(9), 1083-1090 (1997-10-06)
Primary plasmacytoma of the lymph nodes is very rare, and there are fewer than 20 reported cases. These cases appeared to have a better prognosis than other extramedullary plasmacytomas, with rare recurrence and no progression to myeloma after treatment. To
C J van Noesel et al.
Journal of immunology (Baltimore, Md. : 1950), 146(11), 3881-3888 (1991-06-01)
7/8embrane IgM (mIgM) on human B lymphocytes is noncovalently associated with a disulfide-linked dimer that contains phosphoproteins of 47 and 37 kDa. In this study, the biochemical properties and the identity of these Ag receptor-associated components have been addressed. Both

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