00541

Ruthenium Red

for microscopy, 85.0-115.0% (calc. on dry basis, AT)

• Sinónimos: Ammoniated ruthenium oxychloride
• Fórmula lineal: [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
• Número de CAS: 11103-72-3
• Peso molecular: 786.35
• Número de índice de color: 77800
• Número MDL: MFCD00011479
• Código UNSPSC: 12171500
• ID de la sustancia en PubChem: 329747091
• NACRES: NA.47

Propiedades

• grado: for microscopy
• Nivel de calidad: 100
• Análisis: 85.0-115.0% (calc. on dry basis, AT)
• formulario: powder
• impurezas: ~5% water
• solubilidad: water: 10 mg/mL, clear to turbid
• εmax: ≥150 at 529-539 nm
• aplicaciones: diagnostic assay manufacturing; hematology; histology
• temp. de almacenamiento: room temp
• cadena SMILES: N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
• InChI: 1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
• Clave InChI: ZXYSDUPLHOJIOR-UHFFFAOYSA-H

Descripción

Descripción general

Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.

Aplicación

Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.

Inhibits mitochondrial Ca²⁺ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Acciones bioquímicas o fisiológicas

Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable