Y0001812

Sitagliptin phosphate monohydrate

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431
• Fórmula empírica (notación de Hill): C₁₆H₁₅F₆N₅O · H₃PO₄ · H₂O
• Número de CAS: 654671-77-9
• Peso molecular: 523.32
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: sitagliptin
• fabricante / nombre comercial: EDQM
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1
• Clave InChI: GQPYTJVDPQTBQC-KLQYNRQASA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates insulin release and lowers blood glucose.

Aplicación

Sitagliptin phosphate monohydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H319,H373
• Consejos de prudencia: P260 - P264 - P280 - P305 + P351 + P338 - P314 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2 - STOT RE 2
• Órganos de actuación: Liver
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable