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Y0000598

Medroxyprogesterone 17-acetate

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Medroxyprogesterone 17-acetate, 17α-Acetoxy-6α-methylprogesterone, 17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate, 6α-Methyl-17α-acetoxyprogesterone, 6α-Methyl-17α-hydroxyprogesterone acetate

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About This Item

Fórmula empírica (notación de Hill):
C24H34O4
Número de CAS:
71-58-9
Peso molecular:
386.52
Beilstein:
2066112
Número MDL:
MFCD00010483
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329831042
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

medroxyprogesterone

fabricante / nombre comercial

EDQM

mp

206-207 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

formato

neat

cadena SMILES

[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(OC(C)=O)C(C)=O

InChI

1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1

Clave InChI

PSGAAPLEWMOORI-PEINSRQWSA-N

Información sobre el gen

human ... PGR(5241)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Medroxyprogesterone acetate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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Descripción
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Medroxyprogesterone 17-acetate, United States Pharmacopeia (USP) Reference Standard

1378012

Medroxyprogesterone acetate Related Compound A, United States Pharmacopeia (USP) Reference Standard

M0250000

Medroxyprogesterone 17-acetate, European Pharmacopoeia (EP) Reference Standard

Y0001484

Medroxyprogesterone 17-acetate, European Pharmacopoeia (EP) Reference Standard

PHR1589

Medroxyprogesterone 17-acetate, Pharmaceutical Secondary Standard; Certified Reference Material

1378023

Medroxyprogesterone, United States Pharmacopeia (USP) Reference Standard

BP221

Medroxyprogesterone 17-acetate, British Pharmacopoeia (BP) Reference Standard

Pictogramas

Health hazard
GHS08

Palabra de señalización

Warning

Frases de peligro

H351,H413

Clasificaciones de peligro

Aquatic Chronic 4 - Carc. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Léanie Kleynhans et al.
Infection and immunity, 81(4), 1234-1244 (2013-02-06)
The contraceptive depot medroxyprogesterone acetate (DMPA), with progestin as the single active compound, possesses selective glucocorticoid activity and can alter the expression of glucocorticoid receptor-regulated genes. We therefore propose that pharmacological doses of DMPA used for endocrine therapy could have
Lee L Lanza et al.
Obstetrics and gynecology, 121(3), 593-600 (2013-05-03)
Depot medroxyprogesterone acetate (DMPA) reversibly reduces bone mineral density. To estimate the extent to which DMPA might increase fracture risk, we undertook a retrospective cohort study of fractures in DMPA users and users of non-DMPA contraceptives, using the General Practice
Robert A Wild et al.
Menopause (New York, N.Y.), 20(3), 254-260 (2013-02-26)
Our objective was to determine whether metabolic syndrome (MetS) or its components modified the effect of hormone therapy (HT) on the risk of coronary heart disease (CHD) events in the Women's Health Initiative clinical trials. We performed a nested case-control
Richard P H Huijbregts et al.
Endocrinology, 154(3), 1282-1295 (2013-01-29)
Recent observational studies indicate an association between the use of hormonal contraceptives and acquisition and transmission of HIV-1. The biological and immunological mechanisms underlying the observed association are unknown. Depot medroxyprogesterone acetate (DMPA) is a progestin-only injectable contraceptive that is
JoAnn E Manson et al.
JAMA, 310(13), 1353-1368 (2013-10-03)
Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention. To report a comprehensive, integrated overview of findings from the 2 Women's Health Initiative (WHI) hormone therapy trials with extended postintervention
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