PHR1635

Oxcarbazepine

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Oxcarbazepine, 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide, Oxacarbazepine
• Fórmula empírica (notación de Hill): C₁₅H₁₂N₂O₂
• Número de CAS: 28721-07-5
• Peso molecular: 252.27
• Número CE: 249-188-8
• Número MDL: MFCD00865307
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329823525
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. Y0001576; traceable to USP 1483152
• familia API: oxcarbazepine
• CofA: current certificate can be downloaded
• envase: pkg of 1 g
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31
• InChI: 1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
• Clave InChI: CTRLABGOLIVAIY-UHFFFAOYSA-N
• Información sobre el gen: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxcarbazepine is structurally a derivative of carbamazepine and is widely used as an anticonvulsant, antiepileptic and mood stabilizing drug. It is primarily used in the treatment of anxiety, mood disorders, epilepsy and bipolar disorders.

Aplicación

Oxcarbazepine has been used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique and high-performance thin layer chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Anticonvulsant, antineuralgic. Inhibits veratrine-induced transmitter release.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC1421 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable