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P2950000

Primidone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

2-Desoxyphenobarbital, 5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione

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About This Item

Fórmula empírica (notación de Hill):
C12H14N2O2
Número de CAS:
125-33-7
Peso molecular:
218.25
Número MDL:
MFCD00038662
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329820157
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

primidone

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CCC1(C(=O)NCNC1=O)c2ccccc2

InChI

1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

Clave InChI

DQMZLTXERSFNPB-UHFFFAOYSA-N

Información sobre el gen

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Primidone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

1562000

Primidone, United States Pharmacopeia (USP) Reference Standard

1562033

Primidone Related Compound C, United States Pharmacopeia (USP) Reference Standard

1562011

Primidone Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP293

Primidone, British Pharmacopoeia (BP) Reference Standard

Y0002215

Primidone for system suitability, CRS European Pharmacopoeia (EP) Reference Standard

PHR3109

Primidone, pharmaceutical secondary standard, certified reference material

PHR3110

Primidone Related Compound A, pharmaceutical secondary standard, certified reference material

PHR3111

Primidone Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palabra de señalización

Warning

Frases de peligro

H302,H351,H361d

Clasificaciones de peligro

Acute Tox. 4 Oral - Carc. 2 - Repr. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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A Borromei et al.
Minerva medica, 78(22), 1687-1705 (1987-11-30)
A report is presented on 58 patients (46 males, 12 females) all suffering from post-traumatic epilepsy (PTE) and followed up for a minimum of 1 year to maximum of 23 years after the injury (mean 6.3 years). The type and
D F Lehmann
Medical toxicology and adverse drug experience, 2(5), 383-387 (1987-09-01)
Seven cases of crystalluria following primidone overdose have been reported since the 1950s. An eighth case of primidone crystalluria following overdose is presented. Because of low aqueous solubility (600 mg/L at 37 degrees C) which is directly proportional to temperature
Reo Tanoshima et al.
Therapeutic drug monitoring, 35(2), 145-149 (2013-03-19)
A 7.5-year-old girl who was treated with phenobarbital (PHB) for epilepsy was admitted with decreased levels of consciousness. She had been known to have high PHB levels of unknown cause, without symptoms. Her PHB levels were very high, as expected
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