BP197

Hydroxycarbamide

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: Hydroxyurea, Hydroxycarbamide
• Fórmula lineal: NH₂CONHOH
• Número de CAS: 127-07-1
• Peso molecular: 76.05
• Beilstein: 1741548
• Número MDL: MFCD00007943
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: hydroxycarbamide
• formulario: solid
• caducidad: limited shelf life, expiry date on the label
• fabricante / nombre comercial: BP
• aplicaciones: pharmaceutical; pharmaceutical small molecule
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: NC(=O)NO
• InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• Clave InChI: VSNHCAURESNICA-UHFFFAOYSA-N
• Información sobre el gen: human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Hydroxycarbamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Hydroxycarbamide Capsules

Acciones bioquímicas o fisiológicas

Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

Envase

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H340,H361
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Muta. 1B - Repr. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable