BP1094

Cyclophosphamide

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: Cyclophosphamide monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Fórmula empírica (notación de Hill): C₇H₁₅Cl₂N₂O₂P · H₂O
• Número de CAS: 6055-19-2
• Peso molecular: 279.10
• Beilstein: 4678992
• Número MDL: MFCD00149395
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: cyclophosphamide
• Formulario: crystalline
• caducidad: limited shelf life, expiry date on the label
• fabricante / nombre comercial: BP
• mp: 49-51 °C (lit.)
• aplicaciones: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• Clave InChI: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

Acciones bioquímicas o fisiológicas

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations.

Envase

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H301,H340,H350,H360FD
• Consejos de prudencia: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Clasificaciones de peligro: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 235.4 °F - closed cup
• Punto de inflamabilidad (°C): 113 °C - closed cup