92142

Biochanin A

analytical standard

• Sinónimos: 4′-Methylgenistein, 5,7-Dihydroxy-4′-methoxyisoflavone, Genistein 4′-methyl ether, Olmelin
• Fórmula empírica (notación de Hill): C₁₆H₁₂O₅
• Número de CAS: 491-80-5
• Peso molecular: 284.26
• Beilstein: 278107
• Número CE: 207-744-7
• Número MDL: MFCD00006839
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Análisis: ≥95.0% (HPLC)
• caducidad: limited shelf life, expiry date on the label
• mp: 210-213 °C (lit.)
• aplicaciones: food and beverages
• formato: neat
• cadena SMILES: COc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
• InChI: 1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3
• Clave InChI: WUADCCWRTIWANL-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

Biochanin A is an isoflavone phytoestrogen found in red clover (Trifolium pratense) that is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable