901767

PC biotin-PEG3-NHS ester

• Sinónimos: PC biotin-NHS ester
• Fórmula empírica (notación de Hill): C₃₆H₅₂N₆O₁₅S
• Número de CAS: 2353409-93-3
• Peso molecular: 840.89
• Número MDL: MFCD31811520
• Código UNSPSC: 51171641
• NACRES: NA.22

Propiedades

• Formulario: solid
• idoneidad de la reacción: reaction type: click chemistry; reagent type: cross-linking reagent
• mp: 170 °C
• temp. de almacenamiento: −20°C
• cadena SMILES: S1[C@H]([C@H]4NC(=O)N[C@H]4C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)ON3C(=O)CCC3=O)C)OC
• InChI: 1S/C36H52N6O15S/c1-23(56-36(48)57-41-32(45)9-10-33(41)46)24-20-27(51-2)28(21-26(24)42(49)50)55-13-5-8-31(44)38-12-15-53-17-19-54-18-16-52-14-11-37-30(43)7-4-3-6-29-34-25(22-58-29)39-35(47)40-34/h20-21,23,25,29,34H,3-19,22H2,1-2H3,(H,37,43)(H,38,44)(H2,39,
• Clave InChI: WXAMRLAFOFNACR-VTJXTUSFSA-N

Descripción

Aplicación

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm²).

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable