89397

Girard′s reagent T

for HPLC derivatization, LiChropur^™, 99.0-101.0% (AT)

• Sinónimos: (Carboxymethyl)trimethylammonium chloride hydrazide, (Hydrazinocarbonylmethyl)trimethylammonium chloride, Acethydrazide trimethylammonium chloride
• Fórmula lineal: [(CH₃)₃N⁺CH₂CONHNH₂]Cl^-
• Número de CAS: 123-46-6
• Peso molecular: 167.64
• Beilstein: 3727163
• Número CE: 204-629-3
• Número MDL: MFCD00012009
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 329769730
• NACRES: NA.22

Propiedades

• grado: for HPLC derivatization
• Nivel de calidad: 100
• Análisis: 99.0-101.0% (AT)
• formulario: crystals
• calidad: LiChropur^™
• técnicas: HPLC: suitable
• mp: 188-192 °C (dec.) (lit.)
• cadena SMILES: [Cl-].C[N+](C)(C)CC(=O)NN
• InChI: 1S/C5H13N3O.ClH/c1-8(2,3)4-5(9)7-6;/h4,6H2,1-3H3;1H
• Clave InChI: YSULOORXQBDPCU-UHFFFAOYSA-N

Descripción

Aplicación

Girard′s reagent T may be used as a derivatizing reagent for the determination of 5-Formyl-2′-deoxyuridine in cellular DNA samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique. Reducing saccharides can be derivatized by Girard′s reagent T and this can be analyzed by matrix-assisted laser desorption/ionization coupled to time of flight mass spectrometry (MALDI-TOF-MS) technique.

Características y beneficios

• Girard′s reagent T is a chemical derivatization reagent for LC-MS.
• It has carbonyl functional group possessing high proton (cation) affinity that stabilizes a positive charge.       
• It is commonly used in the derivatization of nucleosides.        
• Derivatization reactions in mass spectrometry are used to improve ionization efficiency.
• Derivatization can enhance precise quantitative analysis for profiling of relatively small analyte molecules, particularly in metabolomics.

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Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable