75047

Piperine

analytical standard

• Sinónimos: 1-Piperoylpiperidine
• Fórmula empírica (notación de Hill): C₁₇H₁₉NO₃
• Número de CAS: 94-62-2
• Peso molecular: 285.34
• Beilstein: 90741
• Número CE: 202-348-0
• Número MDL: MFCD00005839
• Código UNSPSC: 85151701
• ID de la sustancia en PubChem: 329766089
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Ensayo: ≥97.0% (HPLC)
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• mp: 131-135 °C (lit.)
• aplicaciones: cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
• InChI: 1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
• Clave InChI: MXXWOMGUGJBKIW-YPCIICBESA-N

Descripción

Descripción general

Piperine is a naturally occurring bioactive alkaloid in pepper, which imparts pungency and bitter flavor to it. It has demonstrated health benefits and exhibits therapeutic properties, which include its role as an antimicrobial, antioxidant, antifungal, immunomodulatory and hepatoprotective agent. The inhibition of drug-metabolizing enzymes in hepatic and pulmonary tissues, and the enhancement of drug bioavailability by this compound are reported. It is also found to play an important role in reducing blood glucose, cholesterol and triglycerides.

Piperine is an amide isolated from the plant, Piper longum. It is a known inhibitor of hepatic and intestinal glucuronidation. Piperine is found to exhibit pharmacological properties like antitumor, antipyretic and anti-inflammatory activities.

Aplicación

Piperine may be used as an analytical reference standard for the quantification of the analyte in:

• Human plasma using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).
• Piper nigrum extract using reversed phase high pressure liquid chromatographic method with UV detection (RP-HPLC-UV).
• Food products using high-performance liquid chromatography with diode array detection (HPLC-DAD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Información de seguridad

• Pictogramas: GHS07,GHS09
• Palabra de señalización: Warning
• Frases de peligro: H302,H411
• Consejos de prudencia: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable