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319112

Sigma-Aldrich

Methylene Blue solution

0.05 wt. % in H2O

Sinónimos:

Loeffler’s Methylene Blue

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About This Item

Fórmula empírica (notación de Hill):
C16H18ClN3S
Número de CAS:
61-73-4
Peso molecular:
319.85
Número de índice de color:
52015
Beilstein:
3641570
Número MDL:
MFCD00012111
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
24858888
NACRES:
NA.47

formulario

liquid

Nivel de calidad

200

concentración

0.05 wt. % in H2O

densidad

0.98 g/mL at 25 °C

λmáx.

665 nm

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

cadena SMILES

[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C

InChI

1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1

Clave InChI

CXKWCBBOMKCUKX-UHFFFAOYSA-M

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Aplicación

Methylene Blue solution has been used to study structural alterations and p53 immune-expression in rats.

Acciones bioquímicas o fisiológicas

Methylene blue (MB) is a highly recognized histological dye. It plays a vital role in microbiology and pharmacology. It has been employed in staining living organisms and in methemoglobinemia treatment. MB exhibits maximum absorption at 664nm. Exposure to methylene blue leads to various health hazards such as increased heart rate, vomiting, shock, Heinz body formation, cyanosis, jaundice, quadriplegia and tissue necrosis in humans

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
MKCK4473
MKCD3437
MKBX9824V
MKBV9924V
MKBQ6919V

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications.
Tardivo JP
Photodiagnosis and Photodynamic Therapy, 2, 175-191 (2005)
Microscopic structural alterations
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
Mazroa S A
International Journal of Clinical and Experimental Pathology, 9, 5346-5356 (2016)
Alexandru Grigoroiu et al.
Scientific reports, 10(1), 3947-3947 (2020-03-05)
Hyperspectral imaging (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve contrast for early cancer detection in the gastrointestinal tract. Motion artefacts during medical endoscopy have traditionally limited HSI application, however, recent developments
J How et al.
Gynecologic oncology, 137(3), 436-442 (2015-04-15)
With the debate over extent of lymphadenectomy in endometrial cancer, sentinel lymph node (SLN) mapping may provide a focused approach to evaluate the most relevant lymph nodes (LN) while minimizing the complications. We evaluated SLN mapping using filtered technetium(99), indocyanine
Alberto Elías-Villalobos et al.
Nature communications, 10(1), 5237-5237 (2019-11-22)
Transcription initiation involves the coordinated activities of large multimeric complexes, but little is known about their biogenesis. Here we report several principles underlying the assembly and topological organization of the highly conserved SAGA and NuA4 co-activator complexes, which share the
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