PC150

Anti-β-Amyloid (1-42) Rabbit pAb

liquid, Calbiochem^®

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: liquid
• no contiene: preservative
• reactividad de especies: human
• envase: antibody small pack of 25 μg
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; avoid repeated freeze/thaw cycles
• isotipo: IgG
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... APP(351)

Descripción

Descripción general

Rabbit polyclonal antibody adsorbed against Aβ_1-40 and Aβ_1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).

Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).

Antibody Target Gene Symbol: APP

Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2

Entrez Gene Name: amyloid beta (A4) precursor protein

Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012,171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)

Mu Entrez ID: 11820

Rat Entrez ID: 54226

This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).

Inmunógeno

Human

a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)

Aplicación

Dot Blot (0.1-0.5 µg/ml)

ELISA (0.1-0.5 µg/ml)

Radioimmunoassay (0.5 µg/ml)

Envase

Please refer to vial label for lot-specific concentration.

Advertencia

Toxicity: Standard Handling (A)

Forma física

In phosphate buffer, pH 7.4.

Reconstitución

Following initial thaw, aliquot and freeze (-20°C).

Otras notas

Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
Borchelt, D.R., et al. 1997. Neuron19, 939.
Citron, M., et al. 1997. Nature Med.3, 67.
Hardy, J. 1997. Trends in Neurosci.20, 154.
Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
Duff, K., et al. 1996. Nature383, 710.
Iwatsubo, T., et al. 1994. Neuron13, 45.
Suzuki, N., et al. 1994. Science264, 133.

This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable