MABF272

Anti-TREM-1, clone 2(1a2) Antibody

clone 2(1a2), from mouse, Atto 550 conjugate

• Sinónimos: Triggering receptor expressed on myeloid cells 1, TREM-1, Triggering receptor expressed on monocytes 1, CD354
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: Atto 550 conjugate
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 2(1a2), monoclonal
• reactividad de especies: human
• técnicas: flow cytometry: suitable
• isotipo: IgG2bκ
• Nº de acceso NCBI: NP_001229518
• Nº de acceso UniProt: Q9NP99
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TREM1(54210)

Descripción

Descripción general

Triggering receptor expressed on myeloid cells 1 (TREM-1) is a membrane bound protein and secreted protein that is expressed by most cells in many tissues including liver, lung, spleen, lymph node, heart, and even spinal cord in response to bacterial and fungal infections. TREM-1 stimulates neutrophil and monocyte mediated inflammatory responses. TREM-1 also triggers pro-inflammatory chemokines and cytokines as well as increases surface expression of cell activation markers like CD11, thus TREM-1 acts as an amplifier of inflammatory responses in response to these pathogens. TREM-1 similarly is a potent LPS response factor and its expression is upregulated by LPS released by bacterial and fungal infections, and thus TREM-1 is a critical mediator of septic shock caused by such infections.

Inmunógeno

Recombinant protein corresponding to human TREM-1.

Aplicación

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

This Anti-TREM-1, clone 2(1a2) Antibody is validated for use in Flow Cytometry for the detection of TREM-1.

Calidad

Evaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 0.25 µg of this antibody detected TREM-1 in human peripheral blood mononuclear cells.

Descripción de destino

26 kDa calculated

Forma física

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to lot specific datasheet.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2