MABC98

Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1

clone 13F9.1, from mouse

• Sinónimos: Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 13F9.1, monoclonal
• reactividad de especies: human
• reactividad de especies (predicha por homología): mouse (immunogen homology)
• técnicas: immunohistochemistry: suitable; western blot: suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_001159687
• Nº de acceso UniProt: Q9H228
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... S1PR5(53637)

Descripción

Descripción general

Sphingosine 1-phosphate receptor 5 (S1PR5 or S1P5), otherwise known as EDG8, is a G-protein coupled receptor which is activated by the lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi/0 alpha and G12 signaling pathways. S1P5 is highly abundant in the brain, particularly in the corpus callosum, but S1P5 has also been detected in the spleen, placenta, lung, aorta, and peripheral blood leukocytes. In the brain, it regulates the transformation of radial glial cells into astrocytes, and the migration of oligodendrocyte precursor cells during development.

Inmunógeno

Recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 5 (S1P5).

Aplicación

Detect Sphingosine 1-phosphate receptor 5 (S1P5) using this Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 validated for use in Western Blotting & IHC.

Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 5 in normal human cerebellum and normal placenta tissue.

Calidad

Evaluated by Western Blot in Daudi cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.

Descripción de destino

~42 kDa observed

Forma física

Format: Purified

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable