MAB5384A4

Anti-NG2 Antibody, clone 132.39, Alexa Fluor^™488 Conjugate

clone 132.39, from mouse, ALEXA FLUOR^™ 488

• Sinónimos: Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, HSN tumor-specific antigen
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• conjugado: ALEXA FLUOR^™ 488
• application: ICC
• clon: 132.39, monoclonal
• reactividad de especies: rat
• citations: 3
• técnicas: immunocytochemistry: suitable

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: ALEXA FLUOR^™ 488
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 132.39, monoclonal
• reactividad de especies: rat
• reactividad de especies (predicha por homología): mouse, human
• técnicas: immunocytochemistry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NP_112284
• Nº de acceso UniProt: Q00657
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CSPG4(1464) ; mouse ... Cspg4(121021) ; rat ... Cspg4(81651)

Descripción

Descripción general

NG2 is a high molecular weight, integral membrane chondroitin sulfate proteoglycan. It is found on the surfaces of an unusual class of glial cells within the developing and mature central nervous system that have the properties of oligodendrocyte precursor cells (i.e., O-2A progenitor cells). NG2 is also found on the surfaces of chondroblasts, proliferating capillary endothelial cells, some human melanoma cell lines, and on leukemic blasts in childhood acute lymphoblastic leukemia. The NG2 proteoglycan is likely to play a role in regulation of cell motility, axon outgrowth and the cellular responses to platelet-derived growth factor.

Especificidad

This antibody recognizes the native, recombinant, and protein from cells which express NG2.

Inmunógeno

Cell line expressing a truncated form of NG2

Aplicación

Anti-NG2 Antibody, clone 132.39, Alexa Fluor^™488 Conjugate detects level of NG2 & has been published & validated for use in ICC.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Calidad

Evaluated by Immunocytochemistry in rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.

Descripción de destino

The unconjugated parent antibody (Cat. No. MAB5384) has an observed molecular weight at ~280 kDa

Forma física

Protein G Purified

Purified mouse monoclonal IgG1 conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Almacenamiento y estabilidad

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análisis

Control
Rat oligodendrocyte precursor cells

Información legal

ALEXA FLUOR is a trademark of Life Technologies

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable