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MAB3632

Sigma-Aldrich

Anti-PPAR gamma 1 and 2 Antibody, phospho-specific (Ser112)

ascites fluid, Chemicon®

Sinónimos:

PPARgamma1 and 2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

ascites fluid

tipo de anticuerpo

primary antibodies

clon

monoclonal

reactividad de especies

mouse, human

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

isotipo

IgG1

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

phosphorylation (pSer112)

Información sobre el gen

human ... PPARG(5468)

Especificidad

Recognizes phosphorylated Peroxisome Proliferator Activated Receptor (PPAR) gamma1 and gamma2.

Inmunógeno

Epitope: phospho-specific (Ser112)
Phosphorylated (serine 112) synthetic peptide from amino acids 107-121 of human PPAR gamma2 (identical to PPAR gamma1). No homology with PPAR alpha or PPAR beta.

Aplicación

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Use Anti-PPAR gamma 1 & 2 Antibody, phospho-specific (Ser112) (mouse monoclonal antibody) validated in ELISA, WB, ICC to detect PPAR gamma 1 & 2 also known as Peroxisome Proliferator Activated Receptor γ 1 & 2.
Western blot: 1:500-1:5,000 on endogenous and recombinant protein.

Immunocytochemistry: 1:500-1:5,000

ELISA: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.

Forma física

Ascites. Liquid. Contains no preservative.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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J Kim et al.
Cellular and molecular life sciences : CMLS, 66(10), 1766-1781 (2009-04-07)
Indenone KR-62776 acts as an agonist of PPAR gamma without inducing obesity in animal models and cells. X-ray crystallography reveals that the indenone occupies the binding pocket in a different manner than rosiglitazone. 2-Dimensional gel-electrophoresis showed that the expression of
Tobias B Huber et al.
Molecular and cellular biology, 23(14), 4917-4928 (2003-07-02)
Mutations of NPHS1 or NPHS2, the genes encoding nephrin and podocin, as well as the targeted disruption of CD2-associated protein (CD2AP), lead to heavy proteinuria, suggesting that all three proteins are essential for the integrity of glomerular podocytes, the visceral
Larry A Denner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(47), 16725-35a-16725-35a (2012-11-24)
We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate cognitive performance. Since extracellular signal-regulated protein kinase mitogen-activated protein
Bo-Mi Kim et al.
International journal of molecular medicine, 43(1), 489-500 (2018-10-27)
Muscat Bailey A grape stalk is an organic waste produced in marked amounts during the vinification of grapes. Previous studies have indicated that grape stalk is rich in bioactive phenolic compounds, and exhibits antioxidant and UV‑protective activities. However, its effects

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