MAB2642

Anti-Fibrillin-2 Antibody, clone 48

clone 48, from mouse

• Sinónimos: fibrillin 2, congenital contractural arachnodactyly, Fibrillin 5
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: 48, monoclonal
• reactividad de especies: human
• técnicas: ELISA: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_001990
• Nº de acceso UniProt: P35556
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FBN2(2201)

Descripción

Descripción general

Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome.

Especificidad

The antibody recognizes Fibrillin-2.

Inmunógeno

Recombinant protein corresponding to human Fibrillin-2.

Aplicación

Anti-Fibrillin-2 Antibody, clone 48 is an antibody against Fibrillin-2 for use in IH, ELISA, IP & IC.

ELISA Analysis: A previous lot was used by an independent laboratory in ELISA (Charbonneau, 2003).

Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Charbonneau, 2003).

Calidad

Evaluated by Immunohistochemistry in liver cancer and papillary serous carcinoma paraffin-embedded tissue sections.

Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Fibrillin-2 in paraffin-embedded tissue sections of liver cancer and papillary serous carcinoma.

Descripción de destino

~ 215 kDa

Forma física

Format: Purified

Nota de análisis

Control
Liver cancer and papillary serous carcinoma tissue

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable