FCMAB203P

Milli-Mark^® Anti-CD64-PE Antibody, clone 10.1

clone 10.1, Milli-Mark^®, from mouse

• Sinónimos: High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RIA, FcgammaRIa, Fc-gamma RI, FcRI
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44
• conjugado: PE
• application: FACS
• clon: 10.1, monoclonal
• reactividad de especies: human
• técnicas: flow cytometry: suitable

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: PE
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 10.1, monoclonal
• reactividad de especies: human
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_000034.1
• Nº de acceso UniProt: P12314
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FCGR1A(2209)

Descripción

Descripción general

CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).

Especificidad

Antibody recognizes Human CD64 antigen.

Inmunógeno

Human rheumatoid synovial fluid cells and monocytes.

Aplicación

Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Calidad

Evaluated by flow cytometry using human PBMCs

Descripción de destino

72 kDa (Sun W, 1997)

Forma física

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Almacenamiento y estabilidad

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Nota de análisis

Control
PBMC′s

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable