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AB9680

Sigma-Aldrich

Anti-GABA A Receptor β 1 Antibody

Chemicon®, from rabbit

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
clon:
polyclonal
application:
WB
reactividad de especies:
human, rat, mouse
técnicas:
western blot: suitable
citations:
4

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human, rat, mouse

fabricante / nombre comercial

Chemicon®

técnicas

western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... GABRB1(2560)

Especificidad

GABAA Receptor beta 1 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor beta 1 subunit in lysates from rat cerebellum and cortex.

Inmunógeno

Fusion protein from the Cytosolic loop of rat the GABAA Receptor beta 1 subunit.

Aplicación

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-GABA A Receptor β 1 Antibody is validated for use in WB for the detection of GABA A Receptor β 1.
Western blot: 1:1,000.

Optimal working dilutions must be determined by the end user.

Ligadura / enlace

Replaces: AB5451

Forma física

Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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R W Olsen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4(5), 1469-1480 (1990-03-01)
The major type of receptor for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), called the GABAA receptor, is a member of a gene superfamily of ligand-gated ion channels. This receptor is a hetero-oligomeric protein composed of several distinct polypeptide types (alpha
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit.
Ogris W, et al.
Biochemical Pharmacology, 68, 1621-1629 (2004)
Angelika Pöltl et al.
Journal of neurochemistry, 87(6), 1444-1455 (2004-01-10)
In cerebellum, 13 different GABA(A) receptor subunits are expressed. The number of different receptor subtypes formed in this tissue, their subunit composition and their quantitative importance so far has not been determined. In the present study, immunodepletion by immunoaffinity chromatography
A K Mehta et al.
Brain research. Molecular brain research, 67(1), 194-199 (1999-04-02)
The anti-alpha1 antibody elicited higher immunoprecipitation (%) values of the [3H]flunitrazepam and [3H]muscimol binding activity in the rat cerebellum vs. cerebral cortex, whereas immunoprecipitation values for [3H]Ro 15-4513 and [3H]zolpidem were comparable in these brain regions. Chronic ethanol administration neither
Alejandra Cabello-Arreola et al.
Genes, 11(3) (2020-03-04)
Suicide is a major public health concern; nevertheless, its neurobiology remains unknown. An area of interest in suicide research is the dorsolateral prefrontal cortex (DLPFC). We aimed to identify altered proteins and potential biological pathways in the DLPFC of individuals

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