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AB5320B

Sigma-Aldrich

Anti-NG2 Chondroitin Sulfate Proteoglycan, Biotin Conjugate Antibody

from rabbit, biotin conjugate

Sinónimos:

Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

conjugado

biotin conjugate

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

rat

reactividad de especies (predicha por homología)

mouse (based on 100% sequence homology), monkey (based on 100% sequence homology), human (based on 100% sequence homology)

técnicas

immunocytochemistry: suitable
immunohistochemistry: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... CSPG4(1464)
mouse ... Cspg4(121021)
rat ... Cspg4(81651)
rhesus monkey ... Cspg4(713086)

Descripción general

NG2 is a high molecular weight, integral membrane chondroitin sulfate proteoglycan. It is found on the surfaces of an unusual class of glial cells within the developing and mature central nervous system that have the properties of oligodendrocyte precursor cells (i.e., O-2A progenitor cells). NG2 is also found on the surfaces of chondroblasts, proliferating capillary endothelial cells, some human melanoma cell lines, and on leukemic blasts in childhood acute lymphoblastic leukemia. The NG2 proteoglycan is likely to play a role in regulation of cell motility, axon outgrowth and the cellular responses to platelet-derived growth factor.

Aplicación

Anti-NG2 Chondroitin Sulfate Proteoglycan, Biotin Conjugate Antibody is an antibody against NG2 Chondroitin Sulfate Proteoglycan for use in IHC, ICC.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in paraffin embedded rat cortex tissue.

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.

Calidad

Evaluated by Immunohistochemistry in cryosections of rat cortex tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in cryosections of rat cortex tissue.

Descripción de destino

The unconjugated parent antibody (Cat. No. AB5320) has an observed molecular weight at ~270-300 kDa

Nota de análisis

Control
Cryosections of rat cortex tissue

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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