AB2265

Anti-VPAC1 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse, human, rat
• técnicas: immunohistochemistry: suitable (paraffin); western blot: suitable
• Nº de acceso NCBI: NP_035833
• Nº de acceso UniProt: P97751
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... VIPR1(7433)

Descripción

Descripción general

The vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1 (VPAC1) is a member of a class II subfamily of G-protein-coupled receptors and has a high affinity for vasoactive intestinal peptide (VIP). VPAC1 has been associated with many different lung cancer cell lines. VPAC1 is thought to be activated by FXR and may contribute to the regulation of bile secretion to protect against gallstone disease. VPAC1 could be used to regulate VIPs and, in turn, inhibit breast cancer growth. VPAC1 has also been implicated in regulation of the anti-inflammatory effects of VIP.

Especificidad

This antibody recognizes VPAC1 at the cytoplasmic domain.

Inmunógeno

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of VPAC1.

Aplicación

Anti-VPAC1 Antibody detects level of VPAC1 & has been published & validated for use in IH(P) & WB.

Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected VPAC1 in ovarian carcinoma tissue.

Research Category
Neuroscience

Research Sub Category
Hormones & Receptors

Calidad

Evaluated by Western Blot in SK-OV-3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected VPAC1 on 10 µg of SK-OV-3 cell lysate.

Descripción de destino

~52 kDa observed. Multiple molecular weights of VPAC1 may be due to glycosylation. (Fabre, C, et al. (1993). Peptides. 14:483-489.)

Forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
SK-OV-3 cell lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable