AB15300

Anti-NECL-1 Antibody

Chemicon^®, from rabbit

• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse
• fabricante / nombre comercial: Chemicon^®
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso UniProt: Q8N126
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CADM3(57863)

Descripción

Descripción general

Nectins are immunoglobulin superfamily adhesion molecules that participate in the organization of epithelial and endothelial junctions. Human and mouse NECL1 share 87.3% identity at the amino acid level (1). NECL1 contains an ectodomain made of three immunoglobulin-like domains, and a cytoplasmic region homologous to those of glycophorin C and contactin-associated protein. NECL1 predominantly expressed in the central nervous system, mainly in neuronal cell bodies in a variety of brain regions including the cerebellum, cerebral cortex and hippocampus. NECL1 localizes to the cell-cell junctions and recruits protein 4.1N to the plasma membranes through its C-terminus, thus may regulate the function of the cell-cell junction.

Especificidad

NECL-1

Inmunógeno

Synthetic Peptide

Aplicación

Detect NECL-1 using this Anti-NECL-1 Antibody validated for use in IH & WB.

Research Category
Neuroscience

Research Sub Category
Neurofilament & Neuron Metabolism

Western Blot Analysis: NECL-1 can be detected at 1/500 dilution. Testing at further dilution was not conducted.

Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.

Optimal working dilutions must be determined by the end user.

Descripción de destino

43 kDa

Forma física

ImmunoAffinity Purified

Purified Antibody in PBS with 0.1% NaN3

Almacenamiento y estabilidad

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Nota de análisis

Control
Tested on Adult mouse brain lysate

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable