AB15014

Anti-Glycine Receptor α3 subunit Antibody

Chemicon^®, from rabbit

• Sinónimos: glycine receptor alpha 3 subunit, glycine receptor, alpha 3, glycine receptor, alpha-3 polypeptide, ligand gated ion channel
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• clon: polyclonal
• application: IHC; WB
• reactividad de especies: mouse, human
• técnicas: immunohistochemistry: suitable; western blot: suitable
• citations: 2

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: mouse, human
• fabricante / nombre comercial: Chemicon^®
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NP_006520.2
• Nº de acceso UniProt: O75311
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GLRA3(8001)

Descripción

Descripción general

Glycine receptor α3 subunit, also known as GLRA3, belongs to the ligand-gated ion channel family. Glycine functions as a inhibitory neurotransmitter throughout the CNS of mammals. The Glycine receptor is a neurotransmitter ligand-gated ion channel. GLRA3 is a pentamer that is composed of ligand binding alpha and structural beta subunits. When glycine binds to the receptor, chloride conductance increases which produces hyperpolarization. It is expressed in the hippocampus, olfactory bulb, and cerebellum. GLRA3 may be involved in human and murine neurological disorders.

Especificidad

Rat (92%) homology.

This antibody recognizes Glycine Receptor α3 subunit.

Inmunógeno

This antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues surrounding the C-terminus of human Glycine Receptor α3 subunit.

Aplicación

Anti-Glycine Receptor α3 subunit Antibody detects level of Glycine Receptor α3 subunit & has been published & validated for use in IH & WB.

Immunohistochemistry Analysis: 1:100-500 dilution from a previous lot detected Glycine Receptor α3 subunit in mouse spinal cord and mouse eye tissue.

Descripción de destino

Approx. 48 kDa

Forma física

Format: Purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable