8.21111

2-Thiazoline-2-thiol

for synthesis

• Sinónimos: 2-Thiazoline-2-thiol, 2-Mercaptothiazoline
• Fórmula empírica (notación de Hill): C₃H₅NS₂
• Número de CAS: 96-53-7
• Peso molecular: 119.21
• Número MDL: MFCD00126013
• Código UNSPSC: 12352113
• Número índice de la CE: 202-512-1
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• formulario: powder
• potencia: 300 mg/kg LD₅₀, oral (Rat)
• pH: 6-7 (20 °C, 10 g/L in H₂O)
• mp: 101-106 °C
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
• Clave InChI: WGJCBBASTRWVJL-UHFFFAOYSA-N

Descripción

Aplicación

• Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
• Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
• Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301
• Consejos de prudencia: P264 - P270 - P301 + P310 - P405 - P501
• Clasificaciones de peligro: Acute Tox. 3 Oral
• Código de clase de almacenamiento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable