476475

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Sinónimos: PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Myr-N-RKRTLRRL-OH, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
• Fórmula empírica (notación de Hill): C₆₀H₁₁₇N₂₁O₁₁
• Peso molecular: 1308.71
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥97% (HPLC)
• Formulario: lyophilized solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated
• solubilidad: water: 5 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC₅₀ = 5 µM) in intact cells.

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC₅₀ = 5 µM).

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target IC₅₀: 5 µM against protein kinase C

Envase

Yes

Advertencia

Toxicity: Standard Handling (A)

Secuencia

Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

Forma física

Supplied as a trifluoroacetate salt.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Otras notas

Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable