171372

Amphiregulin, Human, Recombinant

Amphiregulin, Human, Recombinant, consisting of amino acids 101-198 and is expressed in E. coli. Stimulates the proliferation of various human and mouse keratinocytes.

• Sinónimos: Schwannoma-derived growth factor (SDGF)
• Código UNSPSC: 12352203
• NACRES: NA.77

Propiedades

• recombinante: expressed in E. coli
• Nivel de calidad: 100
• Ensayo: ≥97% (SDS-PAGE)
• Formulario: liquid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• impurezas: <1.0 EU/μg protein Endotoxin
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Recombinant, human amphiregulin (AR) consisting of amino acids 101-198 and expressed in E. coli. Human amphiregulin is able to stimulate the proliferation of various human and mouse keratinocytes, mammary epithelial cells, and some fibroblasts. Shown to be an autocrine growth factor, amphiregulin is also a growth inhibitor for various tumor cells and can bind to the EGF receptor.

Acciones bioquímicas o fisiológicas

ED₅₀ = 5-15 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

Advertencia

Toxicity: Standard Handling (A)

Forma física

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

Reconstitución

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3