165304

D-(–)-2-Amino-5-phosphonopentanoic Acid

≥97% (HPLC), solid, NMDA receptor antagonist, Calbiochem^®

• Sinónimos: D-(–)-2-Amino-5-phosphonopentanoic Acid, D-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate
• Fórmula empírica (notación de Hill): C₅H₁₂NO₅P
• Número de CAS: 79055-68-8
• Peso molecular: 197.13
• Número MDL: MFCD00078839
• Código UNSPSC: 12352106
• NACRES: NA.77

Propiedades

• product name: D-(–)-2-Amino-5-phosphonopentanoic Acid, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.
• Nivel de calidad: 100
• Análisis: ≥97% (HPLC)
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic); protect from light
• color: white
• solubilidad: dilute aqueous base: 1 mg/mL; water: 1 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1
• Clave InChI: VOROEQBFPPIACJ-SCSAIBSYSA-L

Descripción

Descripción general

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
NMDA receptor antagonist

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Irritant (B)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Otras notas

Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
Schulte, M.K., et al. 1994. Brain Res. 649, 203.
Davis, S., et al. 1992. J. Neurosci. 12, 21.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable