164545

7-Amino-4-methylcoumarin

≥98% (HPLC), solid

• Sinónimos: 7-Amino-4-methylcoumarin, AMC, Coumarin 120
• Fórmula empírica (notación de Hill): C₁₀H₉NO₂
• Número de CAS: 26093-31-2
• Peso molecular: 175.18
• Número MDL: MFCD00006868
• Código UNSPSC: 12352200
• NACRES: NA.21

Propiedades

• product name: 7-Amino-4-methylcoumarin, Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity.
• Nivel de calidad: 100
• Análisis: ≥98% (HPLC)
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: yellow
• solubilidad: DMSO: 10 mg/mL; acetone: 10 mg/mL; DMF: soluble
• fluorescencia: λ_ex 365-380 nm; λ_em 430-460 nm
• Condiciones de envío: ambient
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
• Clave InChI: GLNDAGDHSLMOKX-UHFFFAOYSA-N

Descripción

Descripción general

Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity. Useful as a reference standard in enzyme assays.

Reagent used to prepare fluorogenic 7-amino-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzymes (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm). Also useful as a reference standard in enzyme assays.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
Detection of proteolytic enzyme activity

Product does not compete with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Irritant (B)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). DMF and DMSO stock solutions are stable for up to 6 months at -20°C. Acetone stock solutions are stable for up to 1 week at 4°C or -20°C.

Otras notas

Kanaoka, Y., et al. 1982. Chem. Pharm. Bull. 30, 1485.
Zimmerman, M., et al. 1977. Anal. Biochem. 78, 47.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable