14-1109

Human Recombinant Histone H2A.Z

Human recombinant histone H2A.Z expressed in E Coli & purified by Fast Protein Liquid Chromatography (FPLC) & verified mass spectrometry.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propiedades

• origen biológico: Escherichia coli
• Nivel de calidad: 100
• recombinante: expressed in E. coli
• Ensayo: >98% (SDS-PAGE)
• concentración: 1.0 μg/μL
• técnicas: activity assay: suitable
• Condiciones de envío: dry ice

Descripción

Descripción general

Full-length human recombinant H2A.Z expressed in E. Coli and purified by Fast Protein Liquid Chromatography (FPLC ).

The histone variant H2A.Z is a evolutionarily conserved histone variant with a calculated molecular weight of13.5 kDa. This variant replaces conventional histone H2A in a subset of nucleosomes. The nucleosome is the basic unit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histones H2A, H2B, H3 and H4. The histone variant H2AZ has emerged as a key regulator of chromatin function and plays an essential role during mammalian development. H2A.Z is involved in transcriptional regulation, antisilencing, silencing, and genome stability.

Aplicación

Suitable for in vitro chromatin assembly and enzyme activity assays

Forma física

Recombinant protein in a buffer containing 20mM Tris-Cl pH 7.6, 1mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5mM PMSF and 1mM DTT.

Almacenamiento y estabilidad

Stable at -80ºC for 1 year from date of receipt.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable