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Key Documents

07-585

Sigma-Aldrich

Anti-dimethyl-Histone H3 (Arg2) Antibody

serum, Upstate®

Sinónimos:

H3R2me2, Histone H3 (di methyl R2)

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human, chicken

fabricante / nombre comercial

Upstate®

técnicas

inhibition assay: suitable (peptide)
western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

dimethylation (Arg2)

Información sobre el gen

human ... H3F3B(3021)

Especificidad

Broad species cross-reactivity expected
dimethyl-arginine at residue 2 of histone H3

Inmunógeno

peptide containing the sequence AdimRT, corresponding to dimethyl-arginine 2 of human histone H3

Aplicación

Anti-dimethyl-Histone H3 (Arg2) Antibody is a Rabbit Polyclonal Antibody for detection of dimethyl-Histone H3 (Arg2) also known as H3R2me2, Histone H3 (di methyl R2) & has been validated in WB, PIA.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Calidad

routinely evaluated by immunoblot on acid-extracted proteins from chicken erythrocyte cells (Catalog # 13-107)

Descripción de destino

Mr 17kDa

Forma física

Serum
rabbit antiserum containing 0.05% sodium azide, before the addition of glycerol to 30%

Almacenamiento y estabilidad

2 years at -20°C

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases (PRMTs) and regulates fundamental processes in cells, such as gene regulation, RNA processing, translation, and signal transduction. As epigenetic regulators
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The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been
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