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Merck
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Documentos clave

07-544

Sigma-Aldrich

Anti-phospho-nNOS/NOS I (Ser1417) Antibody

Upstate®, from rabbit

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human, rat

envase

antibody small pack of 25 μg

fabricante / nombre comercial

Upstate®

técnicas

western blot: suitable

isotipo

IgG

Nº de acceso NCBI

NM_000620

Nº de acceso UniProt

P29475

Condiciones de envío

dry ice

modificación del objetivo postraduccional

phosphorylation (pSer1417)

Información sobre el gen

human ... NOS1(4842)
rat ... Nos1(24598)

Descripción general

Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS

Especificidad

Predicted to cross-react with mouse, zebrafish and frog based on sequence homology.

Inmunógeno

Peptide corresponding to amino acids surrounding Ser1417 of human neuronal Nitric Oxide Synthase (nNOS).

Aplicación

Anti-phospho-nNOS/NOS I (Ser1417) Antibody is an antibody against phospho-nNOS/NOS I (Ser1417) for use in WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Calidad

Tested

Descripción de destino

Mr 170kDa

Forma física

ImmunoAffinity Purified

Otras notas

Please refer to lot specific datasheet.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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R Socodato et al.
Cell death and differentiation, 21(6), 915-928 (2014-02-18)
During early neurogenesis, retinal neuronal cells display a conserved differentiation program in vertebrates. Previous studies established that nitric oxide (NO) and cGMP accumulation regulate essential events in retinal physiology. Here we used pharmacological and genetic loss-of-function to investigate the effects
Leonardo Nogueira et al.
The Journal of physiology, 589(Pt 18), 4615-4631 (2011-07-27)
The flavanol (-)-epicatechin, a component of cacao (cocoa), has been shown to have multiple health benefits in humans. Using 1-year-old male mice, we examined the effects of 15 days of (-)-epicatechin treatment and regular exercise on: (1) exercise performance, (2)
Z P Chen et al.
American journal of physiology. Endocrinology and metabolism, 279(5), E1202-E1206 (2000-10-29)
AMP-activated protein kinase (AMPK) is a metabolic stress-sensing protein kinase responsible for coordinating metabolism and energy demand. In rodents, exercise accelerates fatty acid metabolism, enhances glucose uptake, and stimulates nitric oxide (NO) production in skeletal muscle. AMPK phosphorylates and inhibits
David J Kosek et al.
Journal of applied physiology (Bethesda, Md. : 1985), 104(5), 1476-1484 (2008-03-22)
The dystrophin-associated protein complex (DAPC) is a scaffold of proteins linking the intracellular cytoskeleton with the extracellular matrix that is integral to structural stability and integrity, signaling and mechanotransduction, and force transmission. We hypothesized that the expression of DAPC component

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