Saltar al contenido
Merck
Todas las fotos(2)

Key Documents

07-146

Sigma-Aldrich

Anti-Histone H2A (acidic patch) Antibody

serum, Upstate®

Sinónimos:

H2A histone family, member Q, histone 2, H2ac, histone IIa, histone cluster 2, H2ac

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

yeast, chicken, human, rat, Saccharomyces cerevisiae, mouse

fabricante / nombre comercial

Upstate®

técnicas

ChIP: suitable
western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

Descripción general

Histone H2A is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the ′beads on a string′ structure.

Especificidad

Broad species cross-reactivity is expected.
Recognizes Histone H2A, Mr 14 kDa.

Inmunógeno

KLH-conjugated, synthetic peptide corresponding to amino acids 88-97 (IRNDEELNKL-C) of human Histone H2A.

Aplicación

Anti-Histone H2A (acidic patch) Antibody is a Rabbit Polyclonal Antibody for detection of Histone H2A (acidic patch) also known as histone 2-H2ac, histone IIa & has been validated in ChIP & WB.
Immunofluorescence:
Recommend Anti-phospho-Histone H2A.X (Ser139), clone JBW301, catalog #05-636.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Calidad

Routinely evaluated by western blot on acid extracts from HeLa cell lysate.

Western Blot Analysis:
1:1000-1:5000 dilutions of this lot detected Histone H2A (acidic patch) in acid extracts from HeLa cell lysate.

Descripción de destino

14 kDa

Forma física

Rabbit antiserum polyclonal IgG in buffer containing 0.05% sodium azide. Frozen solution.
Unpurified

Almacenamiento y estabilidad

Stable for 1 year at -20°C from date of receipt.
For maximum recovery of product, centrifuge the vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Nota de análisis

Control
HeLa cell extract.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor.
Rego MA, Harney JA, Mauro M, Shen M, Howlett NG
Oncogene null
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-? and Wnt/?-catenin signaling pathways.
Xie, XL; Wei, M; Kakehashi, A; Yamano, S; Tajiri, M; Wanibuchi, H
Toxicological Sciences null
Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes.
Stanne TM, Rudenko G
Eukaryotic Cell null
p21 transcription is regulated by differential localization of histone H2A.Z.
Gevry, N; Chan, HM; Laflamme, L; Livingston, DM; Gaudreau, L
Genes & Development null
The Polycomb group protein Ring1b is essential for pectoral fin development.
van der Velden, YU; Wang, L; van Lohuizen, M; Haramis, AP
Development null

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico