Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

T-032

Supelco

(−)-Δ8-THC solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C21H30O2
Número de CAS:
5957-75-5
Peso molecular:
314.46
Número CE:
200-659-6
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

300

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

cannabis testing
cannabis testing

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

O1C(C2C(CC(=CC2)C)c3c1cc(cc3O)CCCCC)(C)C

InChI

1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3

Clave InChI

HCAWPGARWVBULJ-UHFFFAOYSA-N

Categorías relacionadas

Descripción general

A certified solution standard suitable for LC/MS or GC/MS applications in cannabinoid testing, clinical toxicology, forensic analysis, or urine drug testing. Δ8-THC is an impurity in synthetic THC manufacturing processes. Δ8-THC is the double bond isomer of the primary psychoactive ingredient of cannabis called Δ9-tetrahydrocannabinol. This cannabinoid has antiemetic, anxiolytic, appetite-stimulating, and analgesic properties.

Aplicación

The Certified Spiking Solution® is suitable for (−)-Δ8-THC testing by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications. The Certified Reference Material (CRM) in solution can also be used as follows:
  • Multi-analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
  • Separation and estimation of 13 cannabinoids from different cannabis products using isocratic high-performance liquid chromatography (HPLC) in combination with a diode array detector (DAD)
  • Gas chromatographic-mass spectrometric (GC-MS) analysis of ten main cannabinoids from hemp inflorescences following their silylation and esterification for derivatization
  • Quantification of cannabidiol and Δ9-tetrahydrocannabinol in addition to the identification of minor cannabinoids from human plasma samples using ultra-performance liquid chromatography (UHPLC) combined with triple quadrupole mass spectrometry following a liquid-liquid extraction
  • QuEChERS based extraction of 15 cannabinoids from 20 food product samples followed by their quantification by liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Características y beneficios

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Producto relacionado

Referencia del producto
Descripción
Precios

C-045

Cannabidiol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-046

Cannabinol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-084

Cannabidiol-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-115

Cannabinol-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-003

(−)-Δ9-THC-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-005

(−)-trans-Δ9-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-011

(−)-Δ9-THC-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-033

exo-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-047

(±)-Δ9-THC solution, 100 μg/mL in heptane, ampule of 1 mL, Cerilliant®

C-150

Cannabichromenic Acid (CBCA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-153

Cannabinolic Acid (CBNA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

T-111

Tetrahydrocannabivarinic acid (THCVA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-171

Cannabicyclolic Acid (CBLA) solution, 0.5 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-217

Hemp Compliance Mix solution, certified reference material, ampule of 1 mL, Cerilliant®

C-219

Cannabinoid Mixture (Neutrals) - 8 Component solution, 500 μg/mL in methanol (each analyte), certified reference material, ampule of 1 mL, Cerilliant®

T-151

THC-O-Acetate solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-220

Cannabinoid Mixture - 3 Component solution, 1 mg/mL in methanol ((each analyte)), certified reference material, ampule of 1 mL, Cerilliant®

T-153

(-)-delta8-THC-D3 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-218

Cannabinoid Mixture (Acids) - 6 Component solution, 500 μg/mL (1% DIPEA and 0.05% Ascorbic acid in Acetonitrile,each analyte), certified reference material, ampule of 1 mL, Cerilliant®

T-112

11-Nor-9-carboxy-delta9-THCV solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-244

Cannabichromenic Acid (CBCA) solution, 1 mg/mL (1% DIPEA and 0.05% Ascorbic acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

T-159

(6aR, 9S)-delta10-THC solution, 1 mg/mL (Degassed Methanol), certified reference material, ampule of 1 mL, Cerilliant®

T-170

(-)-11-nor-9-Carboxy-delta8-THC solution, 1 mg/mL (Degassed Methanol), certified reference material, ampule of 1 mL, Cerilliant®

T-171

(6aR, 9R)-delta10-THC solution, 1 mg/mL (Degassed Methanol), certified reference material, ampule of 1 mL, Cerilliant®

C-264

(±)-Cannabicyclolic Acid (CBLA) solution, 0.5 mg/mL (0.1% DIPEA, 0.05 Ascorbic Acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

T-182

THC-O-Acetate solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

51.8 °F - closed cup

Punto de inflamabilidad (°C)

11.0 °C - closed cup

Listados normativos

Los listados normativos se proporcionan para los productos químicos principalmente. Para los productos no químicos sólo se puede proporcionar información limitada. Si no hay ninguna entrada, significa que ninguno de los componentes está en la lista. Es obligación del usuario garantizar el uso seguro y legal del producto.

EU REACH Annex XVII (Restriction List)

CAS No.

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Ketan Hippalgaonkar et al.
AAPS PharmSciTech, 12(2), 723-731 (2011-06-04)
The purpose of this study was to investigate the effect of cyclodextrins (CDs) on aqueous solubility, stability, and in vitro corneal permeability of delta-8-tetrahydrocannabinol (Δ(8)-THC). Phase solubility of Δ(8)-THC was studied in the presence of 2-hydroxypropyl-β-cyclodextrin (HPβCD), randomly methylated-β-cyclodextrin (RMβCD)
S H Burstein et al.
Life sciences, 56(23-24), 1991-1998 (1995-01-01)
Binding and photoactivation of a cannabinoid-derived ligand to intact mouse peritoneal cells has resulted in the labelling of a G-protein gamma-subunit. The assignment of structure is based on the product's physical characteristics and its ability to react with a polyclonal
S Muchtar et al.
Ophthalmic research, 24(3), 142-149 (1992-01-01)
delta 8-Tetrahydrocannabinol (delta 8-THC), a known antiglaucoma lipophilic drug, was incorporated in a submicron emulsion for ocular administration. The mean droplet size of the emulsion was 130 +/- 41 nm, and no droplet was larger than 400 nm. No change
B R Martin et al.
Pharmacology, biochemistry, and behavior, 46(2), 295-301 (1993-10-01)
One aspect of cannabinoid structure-activity relationships (SARs) that has not been thoroughly investigated is the aromatic (A) ring. Although halogenation of the side chain enhances potency, our recent observation that iodination of the A ring also enhanced activity was surprising.
Donna A Whyte et al.
Pharmacology, 85(6), 328-335 (2010-06-03)
The primary cannabinoids, Delta(9)-tetrahydrocannabinol (Delta(9)-THC) and Delta(8)-tetrahydrocannabinol (Delta(8)-THC) are known to disturb the mitochondrial function and possess antitumor activities. These observations prompted us to investigate their effects on the mitochondrial O(2) consumption in human oral cancer cells (Tu183). This epithelial
Ver todos los artículos relacionados

Artículos

UHPLC Analysis of Cannabinoids on Ascentis Express C18

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

Cannabinoid Certified Reference Materials (CRMs) for an Improved Testing Accuracy and Traceability

We offer a portfolio of cannabinoid CRMs such as THC and THCA, available as single component solutions or mixes, certified in accordance with ISO 17034 and ISO/IEC 17025 for accurate cannabinoid profiling and potency testing.

Cannabis Testing

The cannabinoids found in the Cannabis plant commonly referred to as marijuana, have grown in popularity for treating a variety of ailments from arthritis, glaucoma, and chronic pain to malnutrition, multiple sclerosis, and cancer.

Workflow for Cannabinoids Analysis in Cannabis Using Chromolith® Monolithic Silica HPLC Column Providing Low Backpressure and Extended Column Lifetime

A comprehensive high performance liquid chromatography-diode array detection (HPLC-DAD) workflow for the analysis of 14 cannabinoids in hemp bud extracts within 10 minutes using robust Chromolith® monolithic silica HPLC columns with low column back pressure.

Ver todo

Protocolos

Analysis of Active Cannabis Compounds in Edible Food Products: Gummy Bears and Brownies

Potency testing in marijuana-infused edibles is an important problem that analytical labs are facing due to the complexity of the involved matrices. Concentration of active ingredients in these edibles can range from a few parts per million to 3.5 parts per thousand. This application demonstrates the extraction and HPLC-UV analysis of the active compounds.

UHPLC Analysis Cannabinoids Ascentis Express

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

Analysis of Active Cannabis Compounds (Cannabinoids) in Edible Food Products: Gummy Bears and Brownies

Rapid potency testing of marijuana-infused edibles using LC/MS on a biphenyl stationary phase detected eleven cannabinoids.

UHPLC (Isocratic) Analysis of 14 Cannabinoids on Ascentis® Express C18

Tetrahydrocannabinolic acid A solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Cannabichromenic Acid (CBCA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL

Global Trade Item Number

Número de referencia del producto (SKU)GTIN
T-032-1ML4061837328978

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico