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S-010

Supelco

Sildenafil solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C22H30N6O4S
Número de CAS:
139755-83-2
Peso molecular:
474.58
Número CE:
200-659-6
Número MDL:
MFCD00867528
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329824411
NACRES:
NA.24

grado

certified reference material

formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

pharmaceutical (small molecule)

formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

O=C1NC(C2=C(OCC)C=CC(S(=O)(N3CCN(C)CC3)=O)=C2)=NC4=C1N(C)N=C4CCC

InChI

1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

Clave InChI

BNRNXUUZRGQAQC-UHFFFAOYSA-N

Información sobre el gen

human ... PDE5A(8654)

Descripción general

Sildenafil is a treatment for erectile dysfunction and pulmonary arterial hypertension. Sold under the trade name Viagra®, sildenafil has a history of abuse, including by athletes as a performance enhancing drug. This Certified Spiking Solution® is applicable for use in urine drug testing, sports testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

Aplicación


  • Effect of topical sildenafil on wound healing and oxidative stress in rats: This study investigates the application of sildenafil in a topical solution form to enhance wound healing and reduce oxidative stress in a rat model, providing insights into its potential therapeutic applications (Tunc and Ercan, 2024).

  • The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications: Research assesses the compatibility of sildenafil solution when combined with various parenteral medications used in neonatal intensive care, suggesting its safe and effective integration for clinical use (De Silva et al., 2024).

  • Changes in Pulmonary Vascular Resistance and Obstruction Score Following Acute Pulmonary Embolism: This study uses sildenafil in a model of acute pulmonary embolism in pigs to evaluate its effects on pulmonary vascular resistance and obstruction, highlighting its potential in managing this condition (Merit et al., 2024).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Viagra is a registered trademark of Pfizer, Inc.

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

A A Kamalov et al.
Urologiia (Moscow, Russia : 1999), (3)(3), 29-30 (2013-08-31)
The article presents the results of the study aimed to the evaluation the efficacy of combination therapy with alpha1-blocker (tamsulosin) and phosphodiesterase type 5 inhibitor (sildenafil) in patients with urination disorders and erectile dysfunction (ED). A pilot observational study involving
G Rocha et al.
Minerva pediatrica, 65(3), 271-278 (2013-05-21)
Over the last two decades, new therapies have emerged for the management of congenital diaphragmatic hernia (CDH). The aim of this paper was to review our experience in the management of newborns diagnosed with CDH over a 14-year period. Review
[Yesterday, Viagra was a medication].
Jean-Yves Nau
Revue medicale suisse, 9(392), 1396-1397 (2013-07-26)
[Yesterday, Viagra was a drug (2) ].
Jean-Yves Nau
Revue medicale suisse, 9(393), 1446-1447 (2013-08-27)
Hamid Mahdiuni et al.
Biophysical chemistry, 175-176, 1-16 (2013-03-19)
Sildenafil was investigated for its interaction with the native and modified human carbonic anhydrase II (hCA II). Modification of exposed histidine side chains with diethyl pyrocarbonate decreased esterase activity of the enzyme. The treatment of both native and modified CA
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