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M-039

Supelco

Meprobamate solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C9H18N2O4
Número de CAS:
57-53-4
Peso molecular:
218.25
Número CE:
200-659-6
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

300

formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

clinical testing

formato

single component solution

temp. de almacenamiento

2-8°C

cadena SMILES

CCCC(C)(COC(N)=O)COC(N)=O

InChI

1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)

Clave InChI

NPPQSCRMBWNHMW-UHFFFAOYSA-N

Información sobre el gen

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Categorías relacionadas

Descripción general

Meprobamate is marketed as an anti-anxiety drug and muscle relaxant under the trade names Milltown, Meprospan, and Equanil. This Certified Spiking Solution® is suitable for GC/MS or LC/MS testing applications in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.

Aplicación


  • Meprobamate solution for neurotransmitter research: Meprobamate is investigated for its impact on the uptake and translocation of pharmaceutical compounds by vegetables, providing insights into environmental interactions and bioaccumulation potential. This research is valuable for understanding how sedative compounds like meprobamate interact with biological systems beyond their primary pharmacological targets (Wu et al., 2013).

  • High-purity meprobamate for in vitro studies: The CNS activities of various plant extracts, including their interaction with CNS depressants like meprobamate, are studied to assess potential synergistic effects and therapeutic applications. Such research is crucial for pharmaceutical and neurological studies, providing a basis for developing new therapeutic strategies (Pal and Samanta, 2011).

  • Meprobamate as an anxiolytic agent in pharmacological research: Investigations into the CNS depressant activities of different plant roots highlight the importance of meprobamate as a comparative standard in pharmacological research. These studies are essential for validating the efficacy and safety of new anxiolytic candidates (Pal et al., 2011).

  • Meprobamate solution for GABA receptor assay: The evaluation of CNS activities of various natural extracts in comparison with known CNS depressants like meprobamate offers valuable data on their mechanisms of action, particularly concerning GABAergic activity. This research supports the use of meprobamate as a benchmark in neuropharmacological assays (Pal et al., 2009).

  • Meprobamate research compound for biochemistry labs: Studies on the CNS effects of botanical extracts using meprobamate as a reference drug help delineate the pathways involved in CNS depression and provide a pharmacological basis for the use of these plants in traditional medicine. This kind of research underpins the development of novel anxiolytic drugs derived from natural sources (Pal, 2008).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

Listados normativos

Los listados normativos se proporcionan para los productos químicos principalmente. Para los productos no químicos sólo se puede proporcionar información limitada. Si no hay ninguna entrada, significa que ninguno de los componentes está en la lista. Es obligación del usuario garantizar el uso seguro y legal del producto.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Arun Kumar et al.
Regulatory toxicology and pharmacology : RTP, 57(2-3), 146-156 (2010-02-16)
This study presents a step-wise development of a quantitative pharmaceutical risk assessment (QPhRA, hereafter) framework, including Monte Carlo uncertainty analysis for meprobamate, carbamazepine, and phenytoin during (1) accidental exposures of stream water and fish consumption and (2) direct ingestion of
Iain M McIntyre et al.
Journal of analytical toxicology, 36(3), 177-181 (2012-03-16)
Carisoprodol is a therapeutic and occasionally abused centrally acting muscle relaxant. We compare central blood and liver concentrations of carisoprodol and the metabolite meprobamate to concentrations in peripheral blood in 11 medical examiner cases. Specimens were initially screened for alcohol
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