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Merck

LM1000

Avanti

12:0-13:0 PC

Avanti Research - A Croda Brand LM1000, methanol solution

Sinónimos:

1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C33H66NO8P
Número de CAS:
Peso molecular:
635.85
Código UNSPSC:
12352211
NACRES:
NA.25

formulario

methanol solution

envase

pkg of 1 × 1 mL (LM1000-1EA)

fabricante / nombre comercial

Avanti Research - A Croda Brand LM1000

concentración

~10 μg/mL (Refer to C of A for lot specific concentration.)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)=O

Descripción general

Phospholipids are major structural biomolecules found in biological membranes. Phosphocholine (PC) is an intermediate of phosphatidylcholine synthesis catalyzed by choline kinase.

Aplicación

12:0-13:0 PC or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine has been used:
  • as an internal standard in liquid chromatography/mass spectrometry (LC/MS) analysis
  • as a lipid standard for phospholipid quantification by MS
  • as an internal standard for the retention time recalibration during LC-MS data processing
  • as an MS grade lipid standard for lipid extraction from macrophages

Acciones bioquímicas o fisiológicas

Phospholipids participate in protein mediated intracellular and extracellular signaling processes.

Envase

2 mL Amber Glass Sealed Ampule (LM1000-1EA)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Akifumi Shiomi et al.
Bioscience, biotechnology, and biochemistry, 84(3), 583-593 (2019-11-26)
Fish cell lines are widely used for the studies of developmental biology, virology, biology of aging, and nutrition physiology. However, little is known about their physicochemical properties. Here, we report the phospholipid compositions and mechanical properties of cell membranes derived
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL
Bingpeng Yan et al.
International journal of molecular sciences, 20(23) (2019-11-30)
Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most common causes of hand, foot, and mouth disease. Severe EV-A71 and CV-A16 infections may be associated with life-threatening complications. However, the pathogenic mechanisms underlying these severe clinical and pathological features
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced

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