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Documentos clave

890717O

Avanti

14:1 EPC (Tf Salt)

Avanti Research™ - A Croda Brand 890717O

Sinónimos:

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

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About This Item

Fórmula empírica (notación de Hill):
C39H73F3NO11PS
Número de CAS:
1246304-44-8
Peso molecular:
852.03
Número MDL:
MFCD00133433
Código UNSPSC:
12352211
NACRES:
NA.25

Formulario

liquid

envase

pkg of 1 × 10 mg (890717O-10mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 890717O

tipo de lípido

transfection
cationic lipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.

Acciones bioquímicas o fisiológicas

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.

Envase

5 mL Clear Glass Sealed Ampule (890717O-10mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Mikhail A Galkin et al.
Journal of visualized experiments : JoVE, (134) (2018-04-24)
Detergents are indispensable for delivery of membrane proteins into 30-100 nm small unilamellar vesicles, while more complex, larger model lipid bilayers are less compatible with detergents. Here we describe a strategy for bypassing this fundamental limitation using fusogenic oppositely charged
Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi et al.
Angewandte Chemie (International ed. in English), 50(31), 7027-7031 (2011-06-24)
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Boris G Tenchov et al.
Biochimica et biophysica acta, 1778(10), 2405-2412 (2008-08-30)
Synthetic cationic lipids can be used as DNA carriers and are regarded to be the most promising non-viral gene carriers. For this investigation, six novel phosphatidylcholine (PC) cationic derivatives with various hydrophobic moieties were synthesized and their transfection efficiencies for
Rumiana Koynova et al.
Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)
Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy
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