870865P

BMP22

Avanti Polar Lipids, powder

• Sinónimos: 4-pentadecylbenzylphosphonic acid
• Fórmula empírica (notación de Hill): C₂₂H₃₉O₃P
• Número de CAS: 1306684-90-1
• Peso molecular: 382.52
• Código UNSPSC: 12352211

Propiedades

• Análisis: 99% (TLC)
• formulario: powder
• envase: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• fabricante / nombre comercial: Avanti Polar Lipids
• tipo de lípido: bioactive lipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

Descripción

Descripción general

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Acciones bioquímicas o fisiológicas

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

Envase

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable