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860533P

Avanti

C16 Ceramide-1-Phosphate (d18:1/16:0)

Avanti Research™ - A Croda Brand 860533P, powder

Sinónimos:

N-palmitoyl-ceramide-1-phosphate (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C34H71N2O6P
Número de CAS:
1246303-22-9
Peso molecular:
634.91
Código UNSPSC:
12352211
NACRES:
NA.25

Formulario

powder

envase

pkg of 1 × 1 mg (860533P-1mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 860533P

tipo de lípido

sphingolipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

InChI

1S/C34H68NO6P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(36)32(31-41-42(38,39)40)35-34(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h27,29,32-33,36H,3-26,28,30-31H2,1-2H3,(H,35,37)(H2,38,39,40);1H3/b29-27+;/t32-,33+;/m0./s1

Clave InChI

RCRVTEZMCBPWGN-YWBCJBABSA-N

Descripción general

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate is a natural long chain ceramide.

Aplicación

C16 Ceramide-1-Phosphate (d18:1/16:0) or N-palmitoyl-ceramide-1-phosphate has been used in lipid preparation to treat endothelial colony-forming cells (ECFCs) for nuclear morphology analysis. It has also been used as a bioactive lipid in cell migration assay to study its effects on multipotent stromal cell (MSCs) and human umbilical vein endothelial cells (HUVECs).

Envase

5 mL Amber Glass Screw Cap Vial (860533P-1mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

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Certificados de análisis (COA)

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Hebe Agustina Mena et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(10), e219-e232 (2019-08-23)
Ceramide 1-phosphate (C1P) is a bioactive sphingolipid highly augmented in damaged tissues. Because of its abilities to stimulate migration of murine bone marrow-derived progenitor cells, it has been suggested that C1P might be involved in tissue regeneration. In the present
V T Hinkovska-Galcheva et al.
The Journal of biological chemistry, 273(50), 33203-33209 (1998-12-05)
Ceramide, a product of agonist-stimulated sphingomyelinase activation, is known to be generated during the phagocytosis of antibody-coated erythrocytes by polymorphonuclear leukocytes. Agonist-stimulated formation of ceramide-1-phosphate is now shown to occur in 32PO4-labeled neutrophils. Ceramide-1-phosphate is formed by a calcium-dependent ceramide
Antonio Gómez-Muñoz et al.
Journal of lipid research, 45(1), 99-105 (2003-10-03)
It was reported previously that ceramide-1-phosphate (Cer-1-P) is mitogenic for fibroblasts (Gómez-Muñoz, A., P. A. Duffy, A. Martin, L. O'Brien, H-S. Byun, R. Bittman, and D. N. Brindley. 1995. Mol. Pharmacol. 47: 883-889; Gómez-Muñoz, A., L. M. Frago, L. Alvarez
A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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