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860520P

Avanti

C20 Ceramide (d18:1/20:0)

Avanti Research™ - A Croda Brand 860520P, powder

Sinónimos:

N-arachidoyl-D-erythro-sphingosine

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About This Item

Fórmula empírica (notación de Hill):
C38H75NO3
Número de CAS:
123482-93-9
Peso molecular:
594.01
Código UNSPSC:
12352211
NACRES:
NA.25

formulario

powder

envase

pkg of 1 × 5 mg (860520P-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 860520P

tipo de lípido

sphingolipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1

Clave InChI

XWBWIAOWSABHFI-NUKVNZTCSA-N

Descripción general

C20 Ceramide (d18:1/20:0) or N-arachidoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with arachidonic acid. Ceramide synthase 2 is responsible for the synthesis of C20 ceramide.

Aplicación

C20 Ceramide (d18:1/20:0) has been used:
  • as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2)
  • as a standard for the quantitation of sphingolipid metabolites
  • to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction

Acciones bioquímicas o fisiológicas

Altered levels of C20 ceramide might function as a potential biomarker for monitoring tumor.

Envase

5 mL Amber Glass Screw Cap Vial (860520P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Donato A Rivas et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(11), 1727-1736 (2012-10-09)
One of the most fundamental adaptive physiological events is the response of skeletal muscle to high-intensity resistance exercise, resulting in increased protein synthesis and ultimately larger muscle mass. However, muscle growth in response to contraction is attenuated in older humans.
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor

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