857127P

17:0 Lyso PA

1-heptadecanoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Sinónimos: heptadecanoyl lysophosphatidic acid; 1-heptadecanoyl-sn-glycero-3-phosphate (sodium salt); PA(17:0/0:0); 17:0 LPA; 110679
• Fórmula empírica (notación de Hill): C₂₀H₄₀O₇PNa
• Número de CAS: 799268-66-9
• Peso molecular: 446.49
• Número MDL: MFCD00672604
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Ensayo: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Formulario: powder
• envase: pkg of 1 × 25 mg (857127P-25mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 857127P
• tipo de lípido: phospholipids; cardiolipins
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100 nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.

Aplicación

17:0 Lyso PA is suitable to use as an internal standard:

• for mass spectrometric determination of lysophosphatidic acid molecular species in mouse peritoneal macrophages
• in the quantification of the lipid species released from extended synaptotagmin 2 (E-SYT2) expressed in mammalian cells by liquid chromatography with tandem mass spectrometry (LC-MS/MS)
• for the extraction of lipids from brain homogenate
• to extract lipids from the stomach washing solution for the determination of lysophosphatidic acid in a mouse stomach fluid

Acciones bioquímicas o fisiológicas

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

Envase

5 mL Amber Glass Screw Cap Vial (857127P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): No data available
• Punto de inflamabilidad (°C): No data available