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Merck

850374C

Avanti

18:1 (Δ6-Cis) PC

1,2-dipetroselenoyl-sn-glycero-3-phosphocholine, chloroform

Sinónimos:

1,2-dipetroselinoyl-sn-glycero-3-phosphocholine; PC(18:1(6Z)/18:1(6Z))

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About This Item

Fórmula empírica (notación de Hill):
C44H84NO8P
Número de CAS:
Peso molecular:
786.11
Código UNSPSC:
51191904
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

liquid

envase

pkg of 1 × 2.5 mL (850374C-25mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand 850374C

concentración

10 mg/mL (850374C-25mg)

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

18:1 (Δ6-Cis) PC (1,2-dipetroselenoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It also has two18 carbon fatty acid chains, each having one cis double bond at the 6th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

18:1 (Δ6-Cis) PC (1,2-dipetroselenoyl-sn-glycero-3-phosphocholine) may be used:
  • to generate sn-1 C18:1(Δ6-cis)- lysophosphatidylcholine (LPC) and sn-1 C18:1(Δ9-cis)-LPC standards for structural characterization of lysophosphatidylcholine (LPC) species by tandem electrospray ionization-linear ion trap-mass spectrometry (ESI-LIT-MS)
  • to study the effect on α-secretase activityin SH-SY5Y membrane
  • in liposome to study the effect of its acyl chain length and bond saturation on pore formation

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.

Envase

5 mL Clear Glass Sealed Ampule (850374C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Clase de riesgo para el agua (WGK)

WGK 3


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Felipe Gazos-Lopes et al.
PLoS neglected tropical diseases, 8(8), e3077-e3077 (2014-08-08)
Trypanosoma cruzi is the causative agent of the life-threatening Chagas disease, in which increased platelet aggregation related to myocarditis is observed. Platelet-activating factor (PAF) is a potent intercellular lipid mediator and second messenger that exerts its activity through a PAF-specific
Marcus O W Grimm et al.
International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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