850345P

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

• Sinónimos: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Fórmula empírica (notación de Hill): C₃₆H₇₂NO₈P
• Número de CAS: 18194-24-6
• Peso molecular: 677.93
• Número MDL: MFCD00036901
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: powder
• envase: pkg of 1 × 1 g (850345P-1g); pkg of 1 × 200 mg (850345P-200mg); pkg of 1 × 25 mg (850345P-25mg); pkg of 1 × 500 mg (850345P-500mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 850345P
• tipo de lípido: phospholipids; cardiolipins
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1
• Clave InChI: CITHEXJVPOWHKC-UMSFTDKQSA-N

Descripción

Descripción general

Dimyristoylphosphatidylcholine (DMPC) belongs to the phosphatidylcholine (PCs) family. It is composed of saturated and symmetric phospholipids with 14 carbon atoms. DMPC is zwitterionic glycerophospholipid and is associated with mammalian membranes.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

14:0 PC (DMPC) has been used:

• in the preparation of liposomes for dissipation monitoring and perforin binding and assembly by Quartz crystal microscopy studies.
• in anthraquinone liposomes generation for spectral studies
• in bicelles preparation along with phosphatidylinositol 4,5-bisphosphate for in vitro reconstitution of β2-adrenergic receptor

Acciones bioquímicas o fisiológicas

Dimyristoylphosphatidylcholine (DMPC) in combination with cholesterol is used as biomembrane model. Oral supplementation of DMPC in apolipoprotein (apo) E−null mice, improves high density lipoprotein levels and other lipid profiles, preventing the pathogenesis of atherosclerosis.

Envase

20 mL Clear Glass Screw Cap Vial (850345P-1g)

20 mL Clear Glass Screw Cap Vial (850345P-500mg)

5 mL Amber Glass Screw Cap Vial (850345P-200mg)

5 mL Amber Glass Screw Cap Vial (850345P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable