840864C

18:0-22:6 PA

1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphate (sodium salt), chloroform

• Sinónimos: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate (sodium salt); PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); 110619
• Fórmula empírica (notación de Hill): C₄₃H₇₂O₈PNa
• Número de CAS: 474943-30-1
• Peso molecular: 770.99
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Análisis: >99% (TLC)
• formulario: liquid
• envase: pkg of 1 × 2.5 mL (840864C-25mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 840864C
• concentración: 10 mg/mL (840864C-25mg)
• tipo de lípido: phospholipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [H][C@@](COP([O-])(O)=O)(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C43H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-20-21-22-24-26-28-30-32-34-36-38-43(45)51-41(40-50-52(46,47)48)39-49-42(44)37-35-33-31-29-27-25-23-18-16-14-12-10-8-6-4-2;/h5,7,11,13,17,19,21-22,26,28,32,34,41H,3-4,6,8-10,12,14-16,18,20,23-25,27,29-31,33,35-40H2,1-2H3,(H2,46,47,48);/q;+1/p-1/b7-5-,13-11-,19-17-,22-21-,28-26-,34-32-;/t41-;/m1./s1
• Clave InChI: XMCFQIVGOJWNBA-VOYBGDFJSA-M

Descripción

Descripción general

18:0-22:6 PA or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphate (sodium salt) is a sodium salt of phosphatidic acid, with substitution of stearic acid and docosahexaenic acid at the sn-1 and sn-2 positions respectively, in the glycerol backbone.

Aplicación

18:0-22:6 PA or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphate (sodium salt) has been used in liposomes to study its role during coat protein I (COPI) vesicle fission. It has also been used in liposomes to determine the lipid-binding properties of the Praja-1 protein.

Acciones bioquímicas o fisiológicas

Phosphatidic acid (PA) is known to be essential for fission stage of coat protein I (COPI) vesicle formation.

Envase

5 mL Clear Glass Sealed Ampule (840864C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372
• Consejos de prudencia: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órganos de actuación: Central nervous system
• Clase de riesgo para el agua (WGK): WGK 3