840858P

16:0-18:2 PA

1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt), powder

• Sinónimos: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (sodium salt); PA(16:0/18:2(9Z,12Z))
• Fórmula empírica (notación de Hill): C₃₇H₆₈O₈PNa
• Número de CAS: 322647-59-6
• Peso molecular: 694.89
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Análisis: >99% (TLC)
• formulario: powder
• envase: pkg of 1 × 100 mg (840858P-100mg); pkg of 1 × 25 mg (840858P-25mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 840858P
• tipo de lípido: phospholipids; cardiolipins
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C37H69O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35H,3-10,12,14-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b13-11-,18-17-;/t35-;/m1./s1
• Clave InChI: IYNPOFCKGPJAFU-HQFKUYMNSA-M

Descripción

Descripción general

Phosphatidic acid (PA) is an anionic, membrane structural lipid. It is amphipathic in nature containing a polar head group and two long hydrophobic acyl chains. PA acts as a parent compound for more complex membrane phospholipids. 16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate is a sodium salt of phosphatidic acid, with substitution of palmitic acid and linolenic acid at the sn-1 and sn-2 positions respectively, in the glycerol backbone.

Aplicación

16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt) might be used as a standard in thin-layer chromatography (TLC) for the separation of ginger and grapefruit exosome-like nanoparticles (ELN)-derived lipids. It might also be used in filter-blotting assay, to study the interaction of AT-hook motif-containing nuclear localized protein 4 (Ahl4) with PA.

Acciones bioquímicas o fisiológicas

Phosphatidic acid (PA) is a bioactive lipid and acts as a secondary messenger. It is associated with hydrogen peroxide production in the neutrophils. PA stimulates the action of protein kinase for neutrophil respiratory burst. It also participates in Ras mediated signaling pathways. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

Envase

5 mL Clear Glass Sealed Ampule (840858P-100mg)

5 mL Clear Glass Sealed Ampule (840858P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids