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Key Documents

791643C

Avanti

18:1-d7 Lyso PC

Avanti Research™ - A Croda Brand

Sinónimos:

1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C26H45D7NO7P
Número de CAS:
2097561-13-0
Peso molecular:
528.71
Código UNSPSC:
41141825
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

liquid

envase

pkg of 1 × 1 mL (791643C-1mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

concentración

1 mg/mL (791643C-1mg)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Categorías relacionadas

Descripción general

18:1-d7 Lyso PC 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine is a deuterated phospholipid. The lipid lysophosphatidylcholine is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylcholine (LPC) is derived from phosphatidylcholine by the action of enzyme phospholipase A2.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Aplicación

18:1-d7 Lyso PC has been used:
  • as an internal standard in high performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESIMS/MS) for the lipidomics analysis of bone marrow-derived macrophages
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)

Acciones bioquímicas o fisiológicas

Lysophosphatidylcholine (LPC). Elevated levels of LPC is associated with diabetes and cardiovascular diseases. LPC stimulates cytokines and is implicated in allergic disease. It also elicits lysis on membranes.

Envase

5 mL Clear Glass Sealed Ampule (791643C-1mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

791637C

15:0-18:1-d7-PC, Avanti Research™ - A Croda Brand

791638C

15:0-18:1-d7-PE, Avanti Research™ - A Croda Brand

791647C

15:0-18:1-d7 DG, Avanti Research™ - A Croda Brand 791647C

791648C

15:0-18:1-d7-15:0 TG, Avanti Research™ - A Croda Brand 791648C

791639C

15:0-18:1-d7-PS, Avanti Research™ - A Croda Brand

791640C

15:0-18:1-d7-PG, Avanti Research™ - A Croda Brand 791640C

791641C

15:0-18:1-d7-PI, Avanti Research™ - A Croda Brand

791642C

15:0-18:1-d7-PA, Avanti Research™ - A Croda Brand

791644C

18:1-d7 Lyso PE, Avanti Research™ - A Croda Brand 791644C

791646C

18:1-d7 MG, Avanti Research™ - A Croda Brand 791646C

791649C

18:1-d9 SM, Avanti Research™ - A Croda Brand

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using

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